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Humanin

Also called HN, HNG

No single human route established in this referenceAnimal / laboratory reference

Research reference

Animal / laboratory study

Original Humanin neuronal-cell experiments

Cell expression and peptide experiments—not human administration

Cell-survival assay windows

Hashimoto et al., PNAS (2001) ↗

When results may show

Humanin

Evidence gap
When change was measured
A cell-rescue effect is not a human memory or lifespan outcome; human origin of the sequence does not make the experiment a human dosing trial.
When to assess
Cell-survival assay windows
Conditions and limitations
Cultured neuronal cells with Alzheimer-related insults. No human starting amount, course length, cycling, mixing volume or time-to-result is established by this experiment. Modified Humanin analogues are separate materials.
When to stop
The measured study window is not a validated personal quit rule. Do not increase or prolong exposure because an expected result is absent; severe or persistent reactions need prompt clinical review.

Research timing is descriptive, not a promise or personal instruction. A severe or persistent reaction needs prompt clinical review. This is not medical advice.

Modelled level — 3x per week

1× is the peak after a single dose.

Steady-state peak
1.00× single dose

Read off the modelled curve, not an even-interval formula

Time to steady state
3hours

About five half-lives

Administrations
3/ week

Where these numbers come from

  • Hashimoto et al., PNAS (2001)No human starting amount, course length, cycling, mixing volume or time-to-result is established by this experiment. Modified Humanin analogues are separate materials.

Next steps