Glutathione
Also called GSH
Oral (by mouth)Human study reference
Research reference
Human study
Oral glutathione randomized study
Separate 250 mg/day and 1,000 mg/day oral groups
6 months plus a 1-month washout
Richie et al., European Journal of Nutrition (2015) ↗When results may show
- When change was measured
- Blood/cell glutathione stores were measured at months 1, 3 and 6; many returned to baseline after washout. These are biomarkers, not proof of anti-aging or skin benefit.
- When to assess
- 6 months plus a 1-month washout
- Conditions and limitations
- 54 healthy nonsmoking adults. Oral exposure does not establish an IV or under-the-skin regimen. No injection mixing or shelf life follows from this study.
- When to stop
- The measured study window is not a validated personal quit rule. Do not increase or prolong exposure because an expected result is absent; severe or persistent reactions need prompt clinical review.
Research timing is descriptive, not a promise or personal instruction. A severe or persistent reaction needs prompt clinical review. This is not medical advice.
Key properties
- Formula
- C10H17N3O6S
- Mol. weight
- 307.33 Da
- CAS
- 70-18-8
- PubChem CID
- 124886
External references
Modelled level — 2x per week
1× is the peak after a single dose.
- Steady-state peak
- 0.97× single dose
- Time to steady state
- 1hours
- Administrations
- 2/ week
Read off the modelled curve, not an even-interval formula
About five half-lives
Where these numbers come from
- Richie et al., European Journal of Nutrition (2015)Oral exposure does not establish an IV or under-the-skin regimen. No injection mixing or shelf life follows from this study.