GDF-11
Also called Growth Differentiation Factor 11
No single human route established in this referenceAnimal / laboratory reference
Research reference
Animal / laboratory study
GDF11 skeletal-muscle experiment
Experimental exposures only
Animal muscle-regeneration endpoints
Egerman et al., Cell Metabolism (2015) ↗When results may show
GDF-11
Evidence gap- When change was measured
- This primary paper reported impaired regeneration under its experimental conditions, not a demonstrated human anti-aging benefit.
- When to assess
- Animal muscle-regeneration endpoints
- Conditions and limitations
- Cell and rodent muscle-regeneration experiments. Conflicting model findings do not define a human replacement target, starter or safe course.
- When to stop
- The measured study window is not a validated personal quit rule. Do not increase or prolong exposure because an expected result is absent; severe or persistent reactions need prompt clinical review.
Research timing is descriptive, not a promise or personal instruction. A severe or persistent reaction needs prompt clinical review. This is not medical advice.
Modelled level — every day
1× is the peak after a single dose.
- Steady-state peak
- 1.00× single dose
- Time to steady state
- 5hours
- Administrations
- 7/ week
Read off the modelled curve, not an even-interval formula
About five half-lives
Where these numbers come from
- Egerman et al., Cell Metabolism (2015)Conflicting model findings do not define a human replacement target, starter or safe course.