FOXO4-DRI
Also called FOXO4-D-Retro-Inverso
No single human route established in this referenceAnimal / laboratory reference
Research reference
Animal / laboratory study
FOXO4-DRI senescent-cell experiments
Experimental cell and mouse exposure only
Cell clearance and mouse tissue-function endpoints
Baar et al., Cell (2017) ↗When results may show
FOXO4-DRI
Evidence gap- When change was measured
- Mouse tissue changes do not establish human rejuvenation, a target blood level or a personal success checkpoint.
- When to assess
- Cell clearance and mouse tissue-function endpoints
- Conditions and limitations
- Cultured cells and aging/chemotoxicity mouse models. No human starting amount, course length, cycling, mixing volume or time-to-result is established by this experiment. No animal-to-human dose conversion or repeat cycle is provided.
- When to stop
- The measured study window is not a validated personal quit rule. Do not increase or prolong exposure because an expected result is absent; severe or persistent reactions need prompt clinical review.
Sources: Baar et al., Cell (2017)
Research timing is descriptive, not a promise or personal instruction. A severe or persistent reaction needs prompt clinical review. This is not medical advice.
Modelled level — 3x per week
1× is the peak after a single dose.
- Steady-state peak
- 1.00× single dose
- Time to steady state
- 10hours
- Administrations
- 3/ week
Read off the modelled curve, not an even-interval formula
About five half-lives
Where these numbers come from
- Baar et al., Cell (2017)No human starting amount, course length, cycling, mixing volume or time-to-result is established by this experiment. No animal-to-human dose conversion or repeat cycle is provided.