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Pemvidutide

Also called ALT-801

Subcutaneous (under the skin)Human study reference

Research reference

Human study

MOMENTUM phase 2 trial

Once weekly; separate 1.2, 1.8 and 2.4 mg study groups

48 weeks

MOMENTUM investigator abstract, ADA (2024) ↗

When results may show

When change was measured
Weight was measured over 48 weeks. The source is an investigator conference abstract, not a full methods paper.
When to assess
48 weeks
Conditions and limitations
391 adults with overweight plus a related condition or obesity. A target group is not a starter escalation. No complete titration, mixing volume or personal stopping rule is inferred from this abstract.
When to stop
The measured study window is not a validated personal quit rule. Do not increase or prolong exposure because an expected result is absent; severe or persistent reactions need prompt clinical review.

Research timing is descriptive, not a promise or personal instruction. A severe or persistent reaction needs prompt clinical review. This is not medical advice.

Vial arithmetic

Published research contexts for Pemvidutide describe 1.2–2.4 mg per administration. Descriptive only, not a recommendation.

Modelled level — once a week

1× is the peak after a single dose.

Steady-state peak
1.57× single dose

Read off the modelled curve, not an even-interval formula

Time to steady state
25.0days

About five half-lives

Administrations
1/ week

Where these numbers come from

Next steps