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Eloralintide

Also called LY3841136

Subcutaneous (under the skin)Human study reference

Research reference

Human study

Eloralintide phase 2 trial

Once weekly; separate 1, 3, 6 and 9 mg groups and two escalation groups

48 weeks

Billings et al., Lancet (2025) ↗

When results may show

When change was measured
The primary endpoint was percentage weight change at week 48. Fixed-dose and escalation groups must remain separate.
When to assess
48 weeks
Conditions and limitations
263 adults with obesity or overweight plus a related condition, without type 2 diabetes. The abstract does not establish a complete universal starter schedule, maintenance cycle or seller-product equivalence.
When to stop
The measured study window is not a validated personal quit rule. Do not increase or prolong exposure because an expected result is absent; severe or persistent reactions need prompt clinical review.

Research timing is descriptive, not a promise or personal instruction. A severe or persistent reaction needs prompt clinical review. This is not medical advice.

Vial arithmetic

Published research contexts for Eloralintide describe 1–3 mg per administration. Descriptive only, not a recommendation.

Modelled level — once a week

1× is the peak after a single dose.

Steady-state peak
1.57× single dose

Read off the modelled curve, not an even-interval formula

Time to steady state
25.0days

About five half-lives

Administrations
1/ week

Where these numbers come from

Next steps