PT-141 vs Melanotan-2 (MT-2)
Compare the research, key figures and safety notes.
How they differ
Both switch on the same melanocortin receptors, which is why they share effects like nausea and flushing. PT-141 (bremelanotide) sticks to one of those receptors and is a licensed medicine used now and then. Melanotan-2 hits them more broadly and is better known for tanning; its only human dosing came from a tiny three-person 1996 study, so its top tested-in-people grade is shaky. Both are short-acting, gone within a few hours.
Side by side
| Measure | PT-141 | Melanotan-2 (MT-2) |
|---|---|---|
| Category | Sexual and reproductive health | Sexual and reproductive health |
| Evidence | A · Human dose research | A · Human dose research |
| Route | Subcutaneous | Subcutaneous |
| Half-life | 2.7 h | 1.5 h |
| Typical vial | 10 mg | 10 mg |
| Research amount | 0.5–2 mg | 0.7–2.1 mg |
| Common schedule | Once a week | Every other day |
| Cycle / break | — | No validated schedule / — |
| Studied for | Sexual and reproductive health | Sexual and reproductive health |
These amounts and schedules are figures discussed in research and community reports, shared for learning — not a recommendation and not medical advice. A step-by-step dosing schedule exists only where a human trial backs it; the evidence tier tells you which.
Decay curves, overlaid
Each line is scaled to that compound's own first dose, so the chart shows how each one builds up over time — not how the compounds' doses compare to one another, which these different molecules share no common unit for.
How they combine
Educational reference on commonly-discussed combinations, not medical advice. Combining compounds can change how each behaves — read this as a prompt to research, not a clearance.